5 Things You Should Know Before the Stock Market Opens

NEW YORK (TheStreet) -- U.S. stock futures were lower Wednesday amid continued political turmoil in Greece.

European stocks were mixed while Asian shares finished with losses. Japan's Nikkei 225 index ended down 1.5% at 9,045.06, its lowest close in nearly three months

U.S. stocks on Tuesday dropped as the political turmoil in Greece renewed concerns about the country's ability to meet the terms of its bailout and remain a member of the eurozone.

The Dow Jones Industrial Average fell by 76 points, or 0.6%, to close at 12,932.

The economic calendar in the U.S. Wednesday includes wholesale inventories for March at 10 a.m. EDT, and weekly crude inventories at 10:30 a.m.

Dow component Cisco(CSCO) will report fiscal third-quarter earnings after the closing bell Wednesday, and analysts expect profit of 47 cents a share on revenue of $11.57 billion.

Fellow Dow component Walt Disney(DIS) on Tuesday posted fiscal second-quarter revenue of $9.63 billion, up 6% from last year and ahead of Wall Street's consensus view of $9.56 billion.

Earnings excluding items at the media and entertainment giant came in at 58 cents a share, 3 cents ahead of analysts' estimates.

GlaxoSmithKline (GSK) is going hostile with its $2.6 billion takeover offer for U.S. drugmaker Human Genome Sciences (HGSI) .

GlaxoSmithKline is offering $13 cash for each share of Human Genome, which last month rejected the British company's private offer.

Human Genome shares closed Tuesday at $14.39. GlaxoSmithKline said its offer is an 81% premium to Human Genome's price on April 18, before the private offer was disclosed.

Japanese automaker Toyota(TM) said quarterly profit more than quadrupled and said fiscal-year earnings would soar to 760 billion yen ($9.5 billion), after falling 30% to 283.6 billion yen for the year ended in March.

Toyota's results mark a turnaround from last year when an earthquake and tsunami in Japan hurt production across the globe.