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Top Insider Trades: RH, AMBI, LULU, CYCC

Tickers in this article: AMBI CYCC LULU RH

By Jonathan Moreland, founder of Insider Insights and author of Profit From Legal Insider Trading.

NEW YORK ( TheStreet) -- It is a victory for common sense. Tracking the trading behavior of company executives, directors and large shareholders in the stocks of firms they're registered in as "insiders" has proven to be profitable, according to both academic studies and (more importantly) the experience of professional investors.

Below are lists of the top 10 mainly open-market insider purchases and sales filed at the Securities and Exchange Commission Wednesday, May 22, 2013 as ranked by dollar value. Please note, however, that these are only factual lists, not buy and sell recommendations. Dollar value is only one metric to assess the importance of an insider transaction, and, frankly, often not even the most important metric that determines if an insider transaction is significant.

At InsiderInsights.com, we find new investment ideas just about every day using these and more intricate insider screens to determine where we should focus our subsequent fundamental and technical analysis. And while stocks don't (or shouldn't) move up or down based on insider activity alone, insiders tend to be good indicators of when real stock-moving events like earnings surprises, corporate actions, and new products may be in the offing.

So use these regular Top Insider Trades columns as the initial research tools they are meant to be, and click the links in the tables to analyze a company's or insider's full insider history. Also feel free to contact us with any questions on our proprietary insider data, and how it is best analyzed.

Ambit ( AMBI) Orbimed BO 680,471 5,421,873
Chesapeake ( CHK) Raspino L DIR 25,000 525,466
Opko ( OPK) Frost P CEO,CB,BO 73,500 514,081
Cooper ( COSH) Silver Point BO 7,000 318,388
Cyclacel ( CYCC) Rombotis S G PR,DIR 100,000 300,000
Medtronic ( MDT) Anderson R DIR 4,800 251,134
Walker & Dunlop ( WD) Florance A C DIR 12,500 237,493
Cardiovascular ( CSII) Nelson G D DIR 10,250 189,359
Smtc ( SMTX) Waterfield J DIR 82,700 165,481
Vestin ( VRTB) Shustek M V PR,CEO,DIR 97,191 145,787
Source: Insider Insights
Restoration ( RH) Friedman G G BO 798,028 39,901,400
Lululemon ( LULU) Wilson D J DIR,BO 377,415 30,824,472
Restoration ( RH) Alberini C CEO,DIR,BO 329,536 16,476,800
Western Ref. ( WNR) Foster P L CB,DIR,BO 500,000 16,196,461
Linkedin ( LNKD) Hoffman R DIR,BO 83,334 15,228,152
Cms ( CMS) Russell J G PR,CEO,DIR 250,000 7,187,750
Keynote ( KEYN) Empire BO 364,594 4,659,512
Trimas ( TRS) Tredwell D P DIR 125,000 4,092,000
Southwestern ( SWN) Kerley G D DIR 100,000 3,950,220
Danaher ( DHR) Comas D L VP,CFO 55,000 3,514,060
Source: Insider Insights

Key to Titles: A=Assistant, AI=Affiliated Investor, AO=Accounting Officer, BD=Business Development, BO=Beneficial Owner, CAO=Chief Accounting Officer, CB=Chairman, CCO=Chief Compliance Officer, CEO=Chief Executive Officer, CFO=Chief Financial Officer, CIO=Chief Information Officer, CO=Compliance Officer, COO=Chief Operating Officer, CT=Controller, CTO=Chief Technology Officer, DIR=Director, EVP=Executive Vice President, F=Founder, FO=Financial Officer, GC=General Counsel, HR=Human Resources, IO=Information Officer, IR=Investor Relations, LO=Legal Officer, MD=Managing Director, O=Officer, OO=Operating Officer, PR=President, PT=Partner, REL=Relative of an insider, SEC=Secretary, SH=Shareholder, SO=Sales Officer, TO=Technology Officer, TR=Treasurer, TT=Trustee, VCB=Vice Chairman, VP=Vice President, X=Ex Officer or other title displayed.